Sébastien Neukirch
Institut Jean le Rond d'Alembert
Centre National de la Recherche Scientifique
Université Pierre et Marie Curie
Paris, France

tel: +33 1 44 27 72 61
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e-mail: sebastien.neukirch (-atat-) upmc.fr

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Friction of F-actin knots

Helmut Kirchner and Sébastien Neukirch

Journal of the Mechanical Behavior of Biomedical Materials, 3 (2010) 121-123

Abstract : We use existing data of force-extension experiments on F-actin molecules tied into knots to compute a value of 0.15 for the static friction coefficient for contact between different parts of the same molecule with itself. This estimate for protein-protein friction is relevant for the stabilization of the 273 known proteins with knots, one percent of the structures deposited in the Protein Data Bank.

doi: 10.1016/j.jmbbm.2009.08.005

download the pre-print version : PDF

download the article : PDF